The findings, published in the New England Journal of Medicine, emerged from the genetic analysis of 1,514 patients with vitiligo and 2,813 without it.
Total of seven genes were identified that were linked to vitiligo.
70% of the population in general had the combination that increases the risk of vitiligo, while reducing the risk of malignant melanoma, the most serious form of skin cancer.
The remaining 30% had a different version that increases the risk of melanoma while reducing the potential for vitiligo.
Although everyone has one of the two alternatives, does not guarantee that any of vitiligo or they suffer from melanoma. Similarly, no guarantees of protection, the study added.
The genes identified as associated with autoimmune conditions such as type 1 diabetes, lupus and rheumatoid arthritis.
This led to suggestions of research may even lead to improvements in treatment for vitiligo.
There is currently no cure, although the condition by controlled through steroid creams and ultraviolet light treatment.
But the study said that the future therapy may involve some element of 'calm the immune response.'
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